How is Kartagener syndrome treated?

How is Kartagener syndrome treated?

There is no cure for Kartagener syndrome. Treatment varies based on the signs and symptoms present in each person but may include airway clearance therapy and antibiotics .

Is Kartagener syndrome congenital?

Siewert first described the combination of situs inversus, chronic sinusitis, and bronchiectasis in 1904. However, Manes Kartagener first recognized this clinical triad as a distinct congenital syndrome in 1933.

What symptoms consist of Kartagener syndrome triad?

Kartagener’s syndrome is a rare, autosomal recessive genetic ciliary disorder comprising the triad of situs inversus, chronic sinusitis, and bronchiectasis. The basic problem lies in the defective movement of cilia, leading to recurrent chest infections, ear/nose/throat symptoms, and infertility.

Can people with Kartagener syndrome have kids?

As Kartagener syndrome is a form of PCD, the motility of cilia will be affected by this disease, and as a result, infertility is not uncommon in patients with PCD.

How long can you live with Kartagener syndrome?

Prognosis in PCD is good, with a normal life expectancy [12]. Diagnosis of PCD can be problematic, with wide variation in symptoms and scarcity of diagnostic facilities [4]. Age at presentation in one study varied from 4 months to 51 years [13].

How common is Kartagener syndrome?

Primary ciliary dyskinesia occurs in approximately 1 in 16,000 to 20,000 births. That translates to the incidence of Kartagener syndrome as 1 in 32,000 to 40,000 births.

Can situs inversus be passed down?

Situs inversus is caused by an autosomal recessive genetic condition. An unaffected carrier mother and an unaffected carrier father have a 1 in 4 chance of having a child with situs inversus.

Can Bardet Biedl syndrome be cured?

There is no cure for Bardet-Biedl syndrome . Treatment generally focuses on the specific signs and symptoms in each individual: While there is no therapy for the progressive vision loss, early evaluation by a specialist can help to provide vision aids and mobility training.

Does situs inversus affect fertility?

Kartagener syndrome, by definition, is a triad of situs inversus, bronchiectasis and chronic sinusitis, and is a subdivision of PCD. It can cause abnormal sperm motility and infertility in men, and can also cause infertility in women because of impaired cilia motility in fallopian tubes.

How does Kartagener syndrome affect sperm?

The moveable tails, or flagella, of sperm can also be affected by PCD. This can cause abnormal sperm motility and infertility in men. Women with Kartagener’s syndrome can also be infertile, due to impaired cilia motility in the lining of their fallopian tubes.